The game was found to be quite CPU intensive in some scenarios, especially during traversal and when ray traced reflections are turned on. The PC version was well received by reviewers with it being praised as a good quality port, with some criticism going to performance sometimes not being optimal on certain hardware configurations. Marvel's Spider-Man Remastered released on August 12, 2022, almost two years after it was originally released for the PlayStation 5 in 2020. The PC version improves in a variety of aspects compared to the PlayStation 5 release, including improved shadows, improved ray traced reflections (full resolution instead of half resolution, and more objects can be included in the ray traced reflections), FoV slider, HBAO+, FSR 2.1, XeSS, DLSS 2, DLSS Frame Generation, DLAA, ultrawide screen support, improved texture filtering and an unlocked frame rate. Marvel's Spider-Man Remastered is the first traditional Spider-Man game to release on PC since The Amazing Spider-Man 2 in 2014.

The game and subsequent remaster for PlayStation 5 were developed by Insomniac Games, while the PC version is being developed by Nixxes Software and published by PlayStation PC. Marvel's Spider-Man Remastered is a remastered version of the PlayStation 4 game from 2018.

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